[Multicenter study of satisfaction with fast-dissolving ebastine, 20 mg/ day, in Mexican patients with allergic rhinitis]

Rev Alerg Mex. 2009 Mar-Apr;56(2):36-40.
[Article in Spanish]

Abstract

Background: Allergic rhinitis is an inflammatory disease of the nasal mucosa, with common symptoms, which is essentially characterized by nasal itching, nasal congestion, sneezing, hyaline rhinorrhea and repetitive sneezing. The disease is very common, 15% of the population worldwide suffers it. Among many treatments that have been used to relieve the symptoms of this disease there is a selective inhibitor of H1 receptors, ebastine.

Objective: To evaluate patient satisfaction using the scale of Treatment Satisfaction Questionnaire for Medication (TSQM).

Material and methods: A multicentric, retrospective, observational study performed in 250 Mexican patients with the diagnosis of intermittent allergic rhinitis (IAR) or persistent allergic rhinitis (PER), confirmed by prick test, specific IgE, or both, treated with lyophilised ebastine in fast-dissolving (FDT) 20 mg at any time in the last two months, prescribed for at least two weeks by their doctor to relieve the symptoms of intermittent allergic rhinitis or persistent allergic rhinitis. We used a validated questionnaire assessment scales, TSQM.

Results: The presentation of ebastine fast-dissolving (FDT) is effective and has good tolerability, over 80% of patients reported comfort and satisfaction using it.

Conclusions: Assessment of overall satisfaction, efficacy, tolerability and comfort showed that ebastine in fast-dissolving is an antihistamine with clear benefits to encourage compliance.

Publication types

  • Clinical Trial
  • English Abstract
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Butyrophenones / administration & dosage*
  • Butyrophenones / therapeutic use
  • Female
  • Histamine H1 Antagonists / administration & dosage*
  • Humans
  • Male
  • Mexico
  • Middle Aged
  • Patient Satisfaction
  • Piperidines / administration & dosage*
  • Piperidines / therapeutic use
  • Retrospective Studies
  • Rhinitis, Allergic, Perennial / drug therapy*
  • Rhinitis, Allergic, Seasonal / drug therapy*
  • Solubility
  • Surveys and Questionnaires
  • Time Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Butyrophenones
  • Histamine H1 Antagonists
  • Piperidines
  • ebastine