DNA structure and integrity checkpoints during the cell cycle and their role in drug targeting and sensitivity of tumor cells to anticancer treatment

Chem Rev. 2009 Jul;109(7):2951-73. doi: 10.1021/cr900026u.
No abstract available

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Cell Cycle / drug effects*
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / metabolism
  • DNA Damage*
  • DNA Repair
  • DNA, Neoplasm / chemistry
  • DNA, Neoplasm / metabolism
  • DNA, Neoplasm / physiology
  • Humans
  • Neoplasms / drug therapy*
  • Protein Kinase Inhibitors / chemistry
  • Protein Kinase Inhibitors / pharmacology
  • Signal Transduction

Substances

  • Antineoplastic Agents
  • Cell Cycle Proteins
  • DNA, Neoplasm
  • Protein Kinase Inhibitors