Abstract
N-Acylated beta-amino enones reductively cyclize by treatment with trichlorosilane and a chiral Lewis base catalyst to afford optically active 4H-1,3-oxazines, which can be transformed to other chiral compounds without racemization.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylation
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Amines / chemistry*
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Catalysis
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Cyclization
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Molecular Structure
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Oxazines / chemical synthesis*
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Oxazines / chemistry
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Oxidation-Reduction
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Silanes / chemistry*
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Stereoisomerism
Substances
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Amines
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Oxazines
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Silanes
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trichlorosilane