Bayesian statistical reconstruction for low-dose X-ray computed tomography using an adaptive-weighting nonlocal prior

Comput Med Imaging Graph. 2009 Oct;33(7):495-500. doi: 10.1016/j.compmedimag.2008.12.007. Epub 2009 Jun 9.

Abstract

How to reduce the radiation dose delivered to the patients has always been a important concern since the introduction of computed tomography (CT). Though clinically desired, low-dose CT images can be severely degraded by the excessive quantum noise under extremely low X-ray dose circumstances. Bayesian statistical reconstructions outperform the traditional filtered back-projection (FBP) reconstructions by accurately expressing the system models of physical effects and the statistical character of the measurement data. This work aims to improve the image quality of low-dose CT images using a novel AW nonlocal (adaptive-weighting nonlocal) prior statistical reconstruction approach. Compared to traditional local priors, the proposed prior can adaptively and selectively exploit the global image information. It imposes an effective resolution-preserving and noise-removing regularization for reconstructions. Experimentation validates that the reconstructions using the proposed prior have excellent performance for X-ray CT with low-dose scans.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bayes Theorem
  • Humans
  • Markov Chains
  • Models, Statistical
  • Radiation Dosage*
  • Tomography, X-Ray Computed*