The NGF point-injection for treatment of the sound-perceiving nerve deafness and tinnitus in 68 cases

J Tradit Chin Med. 2009 Mar;29(1):39-42. doi: 10.1016/s0254-6272(09)60029-7.

Abstract

Objective: To observe the therapeutic effects of the point-injection with nerve growth factor (NGF) for the sound-perceiving nerve deafness and tinnitus.

Methods: The 140 cases in this series were randomly divided into a treatment group of 68 cases treated by NGF injection at the points of Yifeng (TE 17) and Wangu (GB 12), and a control group of 72 cases orally taking Xibiling and adenosine triphosphate (ATP) and intramuscular injection with VB1 and VB12.

Results: The total effective rate was 78.6% in the treatment group and 31.8% in the control group, with significant difference between the two groups (P<0.05).

Conclusion: For treating nervous deafness and tinnitus, NGF point-injection may show good therapeutic effects, but inversely proportional to the illness course, age and the extent of hypoacusis.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acupuncture Points*
  • Adenosine Triphosphate / administration & dosage
  • Administration, Oral
  • Adolescent
  • Adult
  • Deafness / drug therapy*
  • Drugs, Chinese Herbal / administration & dosage
  • Female
  • Humans
  • Injections
  • Male
  • Middle Aged
  • Nerve Growth Factor / administration & dosage*
  • Tinnitus / drug therapy*
  • Young Adult

Substances

  • Drugs, Chinese Herbal
  • Adenosine Triphosphate
  • Nerve Growth Factor