NPR1 in Plant Defense: It's Not over 'til It's Turned over

Cell. 2009 May 29;137(5):804-6. doi: 10.1016/j.cell.2009.05.010.

Abstract

NPR1 is a key transcriptional coregulator in plant defense responses. In this issue, Spoel et al. (2009) demonstrate that proteasome-mediated degradation of NPR1 in the nucleus promotes efficient expression of defense response genes following infection and prevents spurious activation of defensive responses in the absence of infection.

Publication types

  • Comment
  • Research Support, N.I.H., Extramural

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / immunology*
  • Arabidopsis Proteins / immunology*
  • Arabidopsis Proteins / metabolism
  • Gene Expression Regulation, Plant
  • Proteasome Endopeptidase Complex / metabolism

Substances

  • Arabidopsis Proteins
  • NPR1 protein, Arabidopsis
  • Proteasome Endopeptidase Complex