Iodine-catalyzed efficient hydrophosphonylation of N-tosyl aldimines

J Org Chem. 2009 Jun 5;74(11):4393-5. doi: 10.1021/jo9003162.

Abstract

Treatment of N-tosyl aldimines with dialkyl trimethylsilyl phosphites at 0 degrees C in the presence of iodine as a catalyst afforded the corresponding sulfonamide phosphonates in excellent yields within 1.5 to 2.5 h.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Imines / chemistry*
  • Iodine
  • Organophosphonates / chemical synthesis
  • Phosphites / chemistry*
  • Sulfonamides / chemical synthesis
  • Tosyl Compounds / chemistry*

Substances

  • Imines
  • Organophosphonates
  • Phosphites
  • Sulfonamides
  • Tosyl Compounds
  • Iodine