Opportunities for microfluidic technologies in synthetic biology

Shelly Gulati; Vincent Rouilly; Xize Niu; James Chappell; Richard I Kitney; Joshua B Edel; Paul S Freemont; Andrew J deMello

doi:10.1098/rsif.2009.0083.focus

Opportunities for microfluidic technologies in synthetic biology

J R Soc Interface. 2009 Aug 6;6 Suppl 4(Suppl 4):S493-506. doi: 10.1098/rsif.2009.0083.focus. Epub 2009 May 27.

Authors

Shelly Gulati¹, Vincent Rouilly, Xize Niu, James Chappell, Richard I Kitney, Joshua B Edel, Paul S Freemont, Andrew J deMello

Affiliation

¹ Department of Chemistry, Imperial College London, London, UK.

Abstract

We introduce microfluidics technologies as a key foundational technology for synthetic biology experimentation. Recent advances in the field of microfluidics are reviewed and the potential of such a technological platform to support the rapid development of synthetic biology solutions is discussed.

Publication types

Review

MeSH terms

Biotechnology / methods
Computational Biology / methods
DNA-Directed RNA Polymerases / chemistry
Equipment Design
Gene Expression Profiling
Genetic Engineering / methods
Green Fluorescent Proteins / chemistry
Humans
Microfluidic Analytical Techniques / methods*
Microfluidics / methods*
Miniaturization / methods
Models, Biological
Polymerase Chain Reaction
Systems Biology / methods

Substances

Green Fluorescent Proteins
DNA-Directed RNA Polymerases