Probiotic properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6

Appl Environ Microbiol. 2009 Jul;75(14):4887-91. doi: 10.1128/AEM.00394-09. Epub 2009 May 22.

Abstract

Exopolysaccharides have prebiotic potential and contribute to the rheology and texture of fermented foods. Here we have analyzed the in vitro bioavailability and immunomodulatory properties of the 2-substituted (1,3)-beta-D-glucan-producing bacterium Pediococcus parvulus 2.6. It resists gastrointestinal stress, adheres to Caco-2 cells, and induces the production of inflammation-related cytokines by polarized macrophages.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Adhesion
  • Caco-2 Cells
  • Cytokines / metabolism
  • Humans
  • Immunologic Factors / pharmacology*
  • Macrophages / immunology
  • Macrophages / microbiology
  • Pediococcus / immunology*
  • Pediococcus / metabolism*
  • Pediococcus / physiology
  • Probiotics / pharmacology*
  • Proteoglycans
  • beta-Glucans / metabolism*

Substances

  • Cytokines
  • Immunologic Factors
  • Proteoglycans
  • beta-Glucans
  • polysaccharide-K