Layered materials with coexisting acidic and basic sites for catalytic one-pot reaction sequences

Ken Motokura; Mizuki Tada; Yasuhiro Iwasawa

doi:10.1021/ja9012003

Layered materials with coexisting acidic and basic sites for catalytic one-pot reaction sequences

J Am Chem Soc. 2009 Jun 17;131(23):7944-5. doi: 10.1021/ja9012003.

Authors

Ken Motokura¹, Mizuki Tada, Yasuhiro Iwasawa

Affiliation

¹ Department of Chemistry, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

PMID: 19456152
DOI: 10.1021/ja9012003

Abstract

Acidic montmorillonite-immobilized primary amines (H-mont-NH(2)) were found to be excellent acid-base bifunctional catalysts for one-pot reaction sequences, which are the first materials with coexisting acid and base sites active for acid-base tamdem reactions. For example, tandem deacetalization-Knoevenagel condensation proceeded successfully with the H-mont-NH(2), affording the corresponding condensation product in a quantitative yield. The acidity of the H-mont-NH(2) was strongly influenced by the preparation solvent, and the base-catalyzed reactions were enhanced by interlayer acid sites.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acids / chemistry*
Alkalies / chemistry*
Amines / chemistry*
Catalysis

Substances

Acids
Alkalies
Amines