Cardiac surgery for symptomatic carcinoid heart disease in conjunction with adjunctive therapy is being increasingly shown to improve the long-term outlook of patients with carcinoid heart disease. Herein is reported the case of a female patient with heart failure, secondary to carcinoid heart disease affecting all four cardiac valves, who successfully underwent quadruple valve replacement in the same sitting. The patient made an uneventful postoperative recovery, and had an excellent quality of life at the one-year follow up examination.