Altering trend of clinical characteristics of colorectal cancer: a report of 3,607 cases

Ai Zheng. 2009 Jan;28(1):54-6. Epub 2009 Jan 15.

Abstract

Background and objective: Incidence of colorectal cancer in China has increased since 1980s. The epidemiologic character of colorectal cancer in China is similar to that in high prevalence districts. The distributions among different regions are different, with high incidence in the Eastern coastal regions and low incidence in the Western inland. This study was to explore the clinical characteristics of colorectal cancers in Heilongjiang province in 1981-2005.

Methods: A total of 3607 patients with pathologically confirmed colorectal cancer who were hospitalized to Tumor Hospital of Harbin Medical University, Heilongjiang province, in 1981-2005 were divided into 5-year groups. Their clinical data were analyzed.

Results: The annual hospitalization number of colorectal cancer patients in 1985-2005 was increased by 8.5%. The median age increased by seven years. There was no significant change in the male to female ratio of the patients. The proportion of rectal cancer decreased by 13.6%, while the proportions of both right and left hemi-colon cancers increased by 6.8%; the proportion of colorectal cancer at Dukes' A increased by 3.8%, while the proportion of colorectal cancer at Dukes' D decreased by 8.1%.

Conclusions: In the past 25 years, the incidence of colorectal cancer has increased in Heilongjiang province with an increase in median age; the male to female ratio has no significant change. The incidence of rectal cancer and proportion of Dukes' A cancer have increased.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • China / epidemiology
  • Colorectal Neoplasms / epidemiology*
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Time Factors