Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

J Clin Microbiol. 2009 Jul;47(7):2260-4. doi: 10.1128/JCM.00544-09. Epub 2009 May 13.

Abstract

Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Transposable Elements*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics*
  • Molecular Sequence Data
  • Mycobacterium avium subsp. paratuberculosis / classification*
  • Mycobacterium avium subsp. paratuberculosis / genetics*
  • Polymorphism, Single Nucleotide*
  • Sequence Analysis, DNA

Substances

  • DNA Transposable Elements
  • DNA, Bacterial

Associated data

  • GENBANK/FJ775181
  • GENBANK/FJ775182