Aging: shall we take the high road?

Curr Biol. 2009 May 12;19(9):R363-4. doi: 10.1016/j.cub.2009.03.040.

Abstract

For ectotherms, lifespan is increased at low temperature and decreased at high temperature. A new study in Caenorhabditis elegans shows that thermosensory neurons can counteract the effects of high temperature on lifespan by controlling the activity of a steroid signaling pathway.

Publication types

  • Comment
  • Review

MeSH terms

  • Aging / physiology*
  • Animals
  • Caenorhabditis elegans / physiology*
  • Longevity / physiology*
  • Models, Biological
  • Temperature*
  • Thermoreceptors / physiology*