Bioglass-based scaffolds with carbon nanotube coating for bone tissue engineering

J Mater Sci Mater Med. 2009 Oct;20(10):2139-44. doi: 10.1007/s10856-009-3770-9. Epub 2009 May 13.

Abstract

Highly porous 45S5 Bioglass-based foam scaffolds were coated with multi-walled carbon nanotubes (CNT) by electrophoretic deposition (EPD) technique. By placing the scaffolds in between the two electrodes of the EPD cell, a CNT coating of up to 1 mum thickness was achieved on the surface throughout the whole three dimensional (3D) matrix. A 0.5 wt% CNT aqueous suspension was used and EPD was carried out at 2.8 V for 10 mins. The compression strength of this CNT/Bioglass composite was measured to be 0.70 MPa. Moreover the increased electrical conductivity of the composite with CNT coating was confirmed. The scaffolds have the potential for applications in bone tissue engineering due to the high bioactivity, nano-roughness in 3D and electrical conductivity provided by the addition of CNT.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Body Fluids / physiology
  • Bone Substitutes / chemical synthesis
  • Bone Substitutes / chemistry
  • Bone Substitutes / pharmacology
  • Ceramics / chemistry*
  • Coated Materials, Biocompatible / chemical synthesis*
  • Coated Materials, Biocompatible / chemistry
  • Coated Materials, Biocompatible / pharmacology
  • Compressive Strength
  • Durapatite / chemistry
  • Durapatite / pharmacokinetics
  • Electric Conductivity
  • Models, Biological
  • Nanotubes, Carbon / chemistry*
  • Porosity
  • Tissue Engineering* / instrumentation
  • Tissue Engineering* / methods
  • Tissue Scaffolds / chemistry*

Substances

  • Bioglass
  • Bone Substitutes
  • Coated Materials, Biocompatible
  • Nanotubes, Carbon
  • Durapatite