How to map billions of short reads onto genomes

Nat Biotechnol. 2009 May;27(5):455-7. doi: 10.1038/nbt0509-455.

Abstract

Mapping the vast quantities of short sequence fragments produced by next-generation sequencing platforms is a challenge. What programs are available and how do they work?

MeSH terms

  • Algorithms*
  • Base Sequence
  • Genome
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA*
  • Software