Identification of boar testis as a source and target tissue of relaxin

Tetsuya Kohsaka; Shinichi Kato; Si Qin; Itaru Minagawa; Keiichiro Yogo; Tatsuo Kawarasaki; Hiroshi Sasada

doi:10.1111/j.1749-6632.2008.03809.x

Identification of boar testis as a source and target tissue of relaxin

Ann N Y Acad Sci. 2009 Apr:1160:194-6. doi: 10.1111/j.1749-6632.2008.03809.x.

Authors

Tetsuya Kohsaka¹, Shinichi Kato, Si Qin, Itaru Minagawa, Keiichiro Yogo, Tatsuo Kawarasaki, Hiroshi Sasada

Affiliation

¹ Laboratory of Animal Reproduction, Faculty of Agriculture, Shizuoka University, Shizuoka, Japan. t-kohsaka@agr.shizuoka.ac.jp

PMID: 19416187
DOI: 10.1111/j.1749-6632.2008.03809.x

Abstract

The expression and cellular localization of relaxin and its own receptor, LGR7/RXFP1, were demonstrated in the boar testis, where relaxin was produced by the Leydig cells as 18-kDa pro-relaxin and LGR7/RXFP1 was detected in both Leydig cells and seminiferous epithelial cells, suggesting that a functional relaxin-LGR7/RXFP1 hormone-receptor network operates within the boar testis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Epithelial Cells / metabolism
Immunohistochemistry
In Situ Hybridization
Leydig Cells / metabolism
Male
Receptors, G-Protein-Coupled / metabolism
Relaxin / genetics*
Relaxin / metabolism*
Reverse Transcriptase Polymerase Chain Reaction
Swine / physiology*
Testis / cytology
Testis / metabolism*

Substances

Receptors, G-Protein-Coupled
Relaxin