[NT-proBNP in practice: from chemistry to medicine]

P Jourdain; G Lefèvre; C Oddoze; V Sapin; F Dievart; G Jondeau; C Meune; M Galinier

doi:10.1684/abc.2009.0331

[NT-proBNP in practice: from chemistry to medicine]

Ann Biol Clin (Paris). 2009 May-Jun;67(3):255-71. doi: 10.1684/abc.2009.0331.

[Article in French]

Authors

P Jourdain¹, G Lefèvre, C Oddoze, V Sapin, F Dievart, G Jondeau, C Meune, M Galinier

Affiliation

¹ Service de cardiologie, CH René Dubos, Pontoise.

PMID: 19411228
DOI: 10.1684/abc.2009.0331

Abstract

Since introduction of routine assay for natriuretic peptides, there are a growing number of clinical applications for those new tests. Numerous studies have defined analytical characteristics and clinical interest of NT-proBNP assay. Originally limited to acute heart failure diagnosis in the emergency room, NT-proBNP assay has now a wide number of applications. This review presents the "state of art" of this marker, detailing NT-proBNP physiological recent knowledge and its recognized or investigated clinical applications.

Publication types

English Abstract
Review

MeSH terms

Acute Coronary Syndrome / blood
Acute Coronary Syndrome / diagnosis
Acute Disease
Drug Stability
Heart Failure / blood
Heart Failure / diagnosis*
Humans
Natriuretic Peptide, Brain / blood*
Natriuretic Peptide, Brain / metabolism
Natriuretic Peptide, Brain / therapeutic use
Peptide Fragments / blood*
Peptide Fragments / metabolism
Peptide Fragments / therapeutic use
Protein Precursors / blood*
Protein Precursors / metabolism
Protein Precursors / therapeutic use
Sensitivity and Specificity

Substances

Peptide Fragments
Protein Precursors
pro-brain natriuretic peptide (1-76)
Natriuretic Peptide, Brain