Total synthesis of (+)-conagenin

J Asian Nat Prod Res. 2009;11(3):274-80. doi: 10.1080/10286020902828369.

Abstract

A new approach for the synthesis of the (+)-conagenin has been achieved based on Evans asymmetry syn-aldol reaction and the self-regeneration of stereocenters strategy.

MeSH terms

  • Aldehydes / chemistry
  • Molecular Structure
  • Serine / analogs & derivatives*
  • Serine / chemical synthesis
  • Serine / chemistry
  • Stereoisomerism
  • Streptomyces / chemistry

Substances

  • Aldehydes
  • conagenin
  • Serine
  • 3-hydroxybutanal