Kawasaki Disease update

Indian J Pediatr. 2009 Jan;76(1):71-6. doi: 10.1007/s12098-009-0031-3. Epub 2009 Apr 18.

Abstract

Kawasaki Disease is rapidly becoming the most common cause of acquired heart disease in children in both the developed and developing world. Its etiology remains a mystery but important progress has been made in characterizing the features of the arterial wall and myocardial pathology and long-term clinical consequences. New treatments aimed at modifying the host immune response are currently under study. The genetic influence on susceptibility and disease outcome is an area of active research.

Publication types

  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Coronary Aneurysm / diagnosis
  • Coronary Aneurysm / epidemiology
  • Humans
  • Infliximab
  • Mucocutaneous Lymph Node Syndrome / diagnosis
  • Mucocutaneous Lymph Node Syndrome / drug therapy*
  • Mucocutaneous Lymph Node Syndrome / epidemiology
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / epidemiology
  • Tumor Necrosis Factor-alpha / therapeutic use*
  • Vasculitis / diagnosis
  • Vasculitis / epidemiology

Substances

  • Antibodies, Monoclonal
  • Tumor Necrosis Factor-alpha
  • Infliximab