Abstract
Kawasaki Disease is rapidly becoming the most common cause of acquired heart disease in children in both the developed and developing world. Its etiology remains a mystery but important progress has been made in characterizing the features of the arterial wall and myocardial pathology and long-term clinical consequences. New treatments aimed at modifying the host immune response are currently under study. The genetic influence on susceptibility and disease outcome is an area of active research.
MeSH terms
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Antibodies, Monoclonal / therapeutic use*
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Coronary Aneurysm / diagnosis
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Coronary Aneurysm / epidemiology
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Humans
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Infliximab
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Mucocutaneous Lymph Node Syndrome / diagnosis
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Mucocutaneous Lymph Node Syndrome / drug therapy*
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Mucocutaneous Lymph Node Syndrome / epidemiology
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Myocardial Infarction / diagnosis
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Myocardial Infarction / epidemiology
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Tumor Necrosis Factor-alpha / therapeutic use*
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Vasculitis / diagnosis
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Vasculitis / epidemiology
Substances
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Antibodies, Monoclonal
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Tumor Necrosis Factor-alpha
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Infliximab