Trinorsesquiterpenoids from the root extract of Pentalinon andrieuxii

J Nat Prod. 2009 Apr;72(4):745-8. doi: 10.1021/np800554n.

Abstract

Two unusual trinorsesquiterpenoids, urechitols A (1) and B (2), were isolated from the root extract of Pentalinon andrieuxii, a plant used commonly in Yucatecan traditional medicine to treat leishmaniasis. The structures of 1 and 2 were identified by interpretation of their spectroscopic data and chemical correlation reactions. The relative stereochemistry of 1 was confirmed through an X-ray crystallographic study.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apocynaceae / chemistry*
  • Crystallography, X-Ray
  • Leishmaniasis / drug therapy*
  • Medicine, Traditional
  • Mexico
  • Molecular Conformation
  • Molecular Structure
  • Phytotherapy
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology

Substances

  • Sesquiterpenes
  • urechitol A
  • urechitol B