The fatty acid profile and mineral composition (calcium, magnesium, sodium, phosphorus, potassium, iron, zinc, manganese, silicon, boron, cadmium, chromium, nickel, aluminium, copper, and lead) by Inductively Coupled Plasma-Atomic Emission Spectometry (ICP-AES) and the proximate composition of the body and legs of edible frog (Rana esculenta) were investigated. The fatty acids occurring in the highest proportions in both the body and leg of frogs were mystiric acid (C14:0, 1.13-2.30%), palmitic acid (C16:0, 19.76-23.23%), stearic acid (C18:0, 3.61-6.29%), palmitoleic acid (C16:1, 7.06-13.08%), oleic acid (C18:1n-9 cis, 10.83-16.71%), linoleic acid (C18:2n-6, 6.44-6.71%), gamma-linolenic (C18:3n-6, 0.13-0.27%), linolenic (C18:3n-3, 2.32-3.37%), cis-11,14,17-eicosatrienoic acid (C20:3n-3, 4.71-7.72%), cis-5,8,11,14,17-eicosapentaenoic acid (C20:5n-3, 3.96-6.05%) and cis-4,7,10,13,16,19-docosahexaenoic acid (C22:6n-, 2.77-6.67%). Among the minerals determined, potassium was found to be highest, followed by phosphorus. Calcium, aluminium, cadmium, copper, lead, chromium, nickel, boron, silicon and zinc are found to be lower than the potential toxicity levels.