Abstract
Objective:
Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options.
Material and methods:
E. coli strains isolated from urine during a one-year period were studied. Identification and susceptibility tests were performed.
Results:
A total of 652 isolates were included from patients in two institutions, a healthcare clinic 303 (46.5%) and a hospital 349 ( 53.5%). The antimicrobials with higher resistance rates were ampicillin 67.2%, trimethoprim-sulfametoxazole 59.2%, cefazolin 35.6% and ciprofloxacin 24.7%.
Conclusions:
Resistance to trimethoprim-sulfamethoxazole and ciprofloxacin used for empiric treatment in community urinary infections is high, and there are few available treatment options.
MeSH terms
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Adult
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Ambulatory Care Facilities / statistics & numerical data
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Ampicillin / pharmacology
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use*
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Cefazolin / pharmacology
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Ciprofloxacin / pharmacology
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Community-Acquired Infections / drug therapy
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Community-Acquired Infections / epidemiology
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Community-Acquired Infections / microbiology*
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Drug Resistance, Multiple, Bacterial*
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Escherichia coli / drug effects*
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Escherichia coli / genetics
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Escherichia coli Infections / drug therapy
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Escherichia coli Infections / epidemiology
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Escherichia coli Infections / microbiology*
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Female
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Hospitals, Private / statistics & numerical data
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Humans
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Male
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Mexico / epidemiology
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Middle Aged
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Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology
Substances
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Anti-Bacterial Agents
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Ciprofloxacin
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Ampicillin
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Trimethoprim, Sulfamethoxazole Drug Combination
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Cefazolin