[Antibiotic resistance of Escherichia coli from community-acquired urinary tract infections. What antimicrobial to use?]

Salud Publica Mex. 2009 Mar-Apr;51(2):155-9. doi: 10.1590/s0036-36342009000200012.
[Article in Spanish]

Abstract

Objective: Determine antibiotic resistance of community-acquired uropathogen Escherichia coli and infer therapeutic options.

Material and methods: E. coli strains isolated from urine during a one-year period were studied. Identification and susceptibility tests were performed.

Results: A total of 652 isolates were included from patients in two institutions, a healthcare clinic 303 (46.5%) and a hospital 349 ( 53.5%). The antimicrobials with higher resistance rates were ampicillin 67.2%, trimethoprim-sulfametoxazole 59.2%, cefazolin 35.6% and ciprofloxacin 24.7%.

Conclusions: Resistance to trimethoprim-sulfamethoxazole and ciprofloxacin used for empiric treatment in community urinary infections is high, and there are few available treatment options.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Ambulatory Care Facilities / statistics & numerical data
  • Ampicillin / pharmacology
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use*
  • Cefazolin / pharmacology
  • Ciprofloxacin / pharmacology
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / epidemiology
  • Community-Acquired Infections / microbiology*
  • Drug Resistance, Multiple, Bacterial*
  • Escherichia coli / drug effects*
  • Escherichia coli / genetics
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Female
  • Hospitals, Private / statistics & numerical data
  • Humans
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin
  • Ampicillin
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Cefazolin