Chronic catastrophic-like antiphospholipid syndrome: a “smoldering” variant?

Daniel Athanazio; Maria Cristina Rocha; Túlio Geraldo de Souza e Souza; Natália Oliveira e Silva; Sérgio Jezler; Mittermayer Barreto Santiago

doi:10.1007/s00296-009-0913-8

Chronic catastrophic-like antiphospholipid syndrome: a “smoldering” variant?

Rheumatol Int. 2009 Nov;30(1):123-5. doi: 10.1007/s00296-009-0913-8.

Authors

Daniel Athanazio¹, Maria Cristina Rocha, Túlio Geraldo de Souza e Souza, Natália Oliveira e Silva, Sérgio Jezler, Mittermayer Barreto Santiago

Affiliation

¹ Universidade Federal da Bahia, Salvador, Brazil.

PMID: 19373467
DOI: 10.1007/s00296-009-0913-8

Abstract

Catastrophic antiphospholipid syndrome (CAPS) is characterized by life-threatening diffuse thrombotic manifestations involving particularly small vessels of kidney, lungs, brain and skin. We report a 20-year-old female with systemic lupus erythematosus and secondary antiphospholipid syndrome who presented typical organ and histological involvement as seen in CAPS but with protracted course suggesting a “smoldering” form of the disease.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Antiphospholipid Syndrome / classification
Antiphospholipid Syndrome / diagnosis
Antiphospholipid Syndrome / drug therapy
Antiphospholipid Syndrome / immunology*
Catastrophic Illness
Chronic Disease
Drug Therapy, Combination
Female
Humans
Immunosuppressive Agents / therapeutic use
Lupus Erythematosus, Systemic / complications
Lupus Erythematosus, Systemic / drug therapy
Lupus Erythematosus, Systemic / immunology*
Tomography, X-Ray Computed
Treatment Outcome
Young Adult

Substances

Immunosuppressive Agents