2-(2,2,2-Trifluoroethylidene)-1,3-dithiane monoxide as a trifluoromethylketene equivalent

Suguru Yoshida; Hideki Yorimitsu; Koichiro Oshima

doi:10.1021/ol9004883

2-(2,2,2-Trifluoroethylidene)-1,3-dithiane monoxide as a trifluoromethylketene equivalent

Org Lett. 2009 May 21;11(10):2185-8. doi: 10.1021/ol9004883.

Authors

Suguru Yoshida¹, Hideki Yorimitsu, Koichiro Oshima

Affiliation

¹ Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto-daigaku Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

PMID: 19371075
DOI: 10.1021/ol9004883

Abstract

A method to prepare 2-(2,2,2-trifluoroethylidene)-1,3-dithiane monoxide has been developed, and its interesting reactivity under Pummerer-like conditions is disclosed. The products are useful synthetic intermediates for the synthesis of alpha-trifluoromethyl ketones.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Combinatorial Chemistry Techniques
Hydrocarbons, Fluorinated / chemical synthesis*
Hydrocarbons, Fluorinated / chemistry*
Molecular Structure
Stereoisomerism
Sulfur Compounds / chemical synthesis*
Sulfur Compounds / chemistry

Substances

2-(2,2,2-trifluoroethylidene)-1,3-dithiane monoxide
Hydrocarbons, Fluorinated
Sulfur Compounds