Colonic necrosis due to oral kayexalate in a critically-ill patient

Am J Med Sci. 2009 Apr;337(4):305-6. doi: 10.1097/MAJ.0b013e31818dd715.

Abstract

Kayexalate (sodium polystyrene sulfonate in sorbitol) is commonly used for treatment of hyperkalemia. We describe the case of a critically ill patient who developed colonic necrosis after oral administration of kayexalate.

Publication types

  • Case Reports

MeSH terms

  • Cation Exchange Resins / adverse effects*
  • Cation Exchange Resins / therapeutic use
  • Colon / pathology*
  • Critical Illness
  • Female
  • Humans
  • Hyperkalemia / drug therapy
  • Middle Aged
  • Necrosis / chemically induced*
  • Necrosis / pathology
  • Polystyrenes / adverse effects*
  • Polystyrenes / therapeutic use

Substances

  • Cation Exchange Resins
  • Polystyrenes
  • polystyrene sulfonic acid