UGT1A and irinotecan toxicity: keeping it in the family

J Clin Oncol. 2009 May 20;27(15):2419-21. doi: 10.1200/JCO.2008.20.9478. Epub 2009 Apr 13.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Antineoplastic Agents, Phytogenic / adverse effects*
  • Antineoplastic Agents, Phytogenic / pharmacokinetics
  • Camptothecin / adverse effects
  • Camptothecin / analogs & derivatives*
  • Camptothecin / pharmacokinetics
  • Clinical Trials as Topic
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics
  • Glucuronosyltransferase / genetics*
  • Humans
  • Irinotecan

Substances

  • Antineoplastic Agents, Phytogenic
  • Irinotecan
  • UGT1A1 enzyme
  • Glucuronosyltransferase
  • Camptothecin