Genetic diversity of porcine circovirus type 2 in Korean pigs with postweaning multisystemic wasting syndrome during 2005-2007

J Vet Med Sci. 2009 Mar;71(3):349-53. doi: 10.1292/jvms.71.349.

Abstract

The comparison of nucleotide and deduced amino acid sequence was conducted with 9 porcine circovirus type 2 (PCV2) strains isolated from PCV2-infected pigs with postweaning multisystemic wasting syndrome (PMWS) and 50 tissue samples obtained from PCV2-infected 50 pigs with PMWS during 2005-2007. At amino acid positions 88-89 of the ORF2 gene, 50 Korean PCV2 had amino acids PR/L consistent with group 1 PCV2, whereas 9 Korean PCV2 contained amino acids KI, characteristic of group 2 PCV2. Phylogenetically, 47, 3, 2 and 7 Korean PCV2 belonged to subgroups 1A/B (79.7%), 1C (5.1%), 2D (3.4%) and 2E (11.9%), respectively. Although the predominant Korean PCV2 was subgroup 1A/B, subgroups 1C and 2E were still circulating and subgroup 2D PCV2 were found to be newly emerged in Korea.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Circovirus / classification*
  • Circovirus / genetics*
  • Genetic Variation*
  • Korea / epidemiology
  • Phylogeny
  • Porcine Postweaning Multisystemic Wasting Syndrome / epidemiology
  • Porcine Postweaning Multisystemic Wasting Syndrome / virology*
  • Retrospective Studies