Reduction of surgical site infections by use of pulsatile lavage irrigation after prolonged intra-abdominal surgical procedures

Am J Surg. 2009 Sep;198(3):381-6. doi: 10.1016/j.amjsurg.2008.12.021. Epub 2009 Apr 2.

Abstract

Background: Surgical site infections cause significant postoperative morbidity and may be reduced by pressurized irrigation of high-risk laparotomy wounds before closure. This was a retrospective review (June 2007 to May 2008) from a surgical unit at a tertiary care center.

Methods: Patients undergoing laparotomy extending beyond 4 hours, when a standard wound management strategy was instituted by either simple irrigation or pressurized pulsatile lavage (<15 psi) with saline before closure, were included. The outcome measures were the surgical site infections and factors contributing to them.

Results: The median surgical time for the patients was 8 hours, with 34 wounds managed by simple irrigation and 42 wounds managed by pulse irrigation. Both groups had similar characteristics. Overall there were 15 (20%) surgical site infections. Significantly fewer infections occurred in the pulse irrigation group (10% vs 32%; P = .019). The use of a pulse irrigation device was the only factor associated with a reduction in wound infections (P = .019).

Conclusions: Surgical site infections appear to be reduced with pulsatile lavage irrigation of wounds before skin closure in patients undergoing prolonged intra-abdominal surgeries.

MeSH terms

  • Abdomen / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Female
  • Humans
  • Laparotomy
  • Male
  • Middle Aged
  • Peritoneal Lavage
  • Pressure
  • Pulsatile Flow
  • Retrospective Studies
  • Statistics, Nonparametric
  • Surgical Wound Infection / prevention & control*
  • Therapeutic Irrigation / methods*
  • Time Factors
  • Treatment Outcome
  • Wound Healing