First identification of class A carbapenemase-producing Klebsiella pneumoniae in the Republic of Ireland

Euro Surveill. 2009 Apr 2;14(13):19163.

Abstract

The Klebsiella pneumoniae carbapenemase (KPC) was detected in a carbapenem-resistant respiratory isolate of Klebsiella pneumoniae in an Irish hospital. This is the first report of a KPC-producing isolate in the Republic of Ireland. The isolate was resistant to all beta-lactams. Furthermore, it had reduced susceptibility to three other classes of non-beta-lactam antibiotics. The isolate was not associated with travel abroad. Detection of KPC-producing bacteria has important infection control and public health implications.

MeSH terms

  • Bacterial Proteins / analysis*
  • Bacterial Proteins / genetics
  • Cross Infection / microbiology
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Ireland / epidemiology
  • Klebsiella Infections / drug therapy
  • Klebsiella Infections / epidemiology*
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / enzymology*
  • Klebsiella pneumoniae / isolation & purification
  • Male
  • Middle Aged
  • Penicillanic Acid / analogs & derivatives
  • Penicillanic Acid / therapeutic use
  • Piperacillin / therapeutic use
  • Pneumonia, Bacterial / drug therapy
  • Pneumonia, Bacterial / epidemiology*
  • Pneumonia, Bacterial / microbiology
  • Tazobactam
  • beta-Lactamases / analysis*
  • beta-Lactamases / genetics

Substances

  • Bacterial Proteins
  • Penicillanic Acid
  • beta-Lactamases
  • carbapenemase-2, Klebsiella pneumoniae
  • Tazobactam
  • Piperacillin