Primary non-Hodgkin's lymphoma presenting as radicular syndrome: report of two cases

Rheumatol Int. 2009 Nov;30(1):113-7. doi: 10.1007/s00296-009-0898-3.

Abstract

We report two cases of primary Non-Hodgkin's Lymphoma in the spine leading to radicular compression secondary to infiltration of lumbar body vertebras. The two patients were free of either nodular or other extra-nodular disease. Treatment consisted of chemotherapy alone, one patient have had a cauda equina syndrome and surgical decompression was performed in emergency. The patients were in remission for 20 months after diagnosis. A review is given for the incidence of primary vertebral localization of lymphoma, its diagnosis, treatment and prognosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Back Pain / etiology
  • Biopsy
  • Decompression, Surgical
  • Female
  • Humans
  • Lumbar Vertebrae / pathology*
  • Lymphoma, Non-Hodgkin / complications*
  • Lymphoma, Non-Hodgkin / drug therapy
  • Lymphoma, Non-Hodgkin / pathology
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Polyradiculopathy / etiology*
  • Polyradiculopathy / surgery
  • Radiculopathy / etiology*
  • Radiculopathy / surgery
  • Spinal Neoplasms / complications*
  • Spinal Neoplasms / drug therapy
  • Spinal Neoplasms / pathology
  • Treatment Outcome