Abstract
We report two cases of primary Non-Hodgkin's Lymphoma in the spine leading to radicular compression secondary to infiltration of lumbar body vertebras. The two patients were free of either nodular or other extra-nodular disease. Treatment consisted of chemotherapy alone, one patient have had a cauda equina syndrome and surgical decompression was performed in emergency. The patients were in remission for 20 months after diagnosis. A review is given for the incidence of primary vertebral localization of lymphoma, its diagnosis, treatment and prognosis.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Back Pain / etiology
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Biopsy
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Decompression, Surgical
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Female
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Humans
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Lumbar Vertebrae / pathology*
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Lymphoma, Non-Hodgkin / complications*
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Lymphoma, Non-Hodgkin / drug therapy
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Lymphoma, Non-Hodgkin / pathology
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Neoplasm Invasiveness
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Polyradiculopathy / etiology*
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Polyradiculopathy / surgery
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Radiculopathy / etiology*
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Radiculopathy / surgery
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Spinal Neoplasms / complications*
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Spinal Neoplasms / drug therapy
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Spinal Neoplasms / pathology
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Treatment Outcome