Trichothecenes in cereal grains

Int J Mol Sci. 2009 Jan;10(1):147-173. doi: 10.3390/ijms10010147. Epub 2009 Jan 6.

Abstract

Trichothecenes are sesquiterpenoid mycotoxins associated with fusarium head blight (FHB) of cereals, with worldwide economic and health impacts. While various management strategies have been proposed to reduce the mycotoxin risk, breeding towards FHB-resistance appears to be the most effective means to manage the disease, and reduce trichothecene contamination of cereal-based food products. This review provides a brief summary of the trichothecene synthesis in Fusarium species, their toxicity in plants and humans, followed by the current methods of screening and breeding for resistance to FHB and trichothecene accumulation.

Keywords: Trichothecene; cereal grain; fusarium head blight.

Publication types

  • Review

MeSH terms

  • Disease Resistance / genetics
  • Edible Grain / microbiology*
  • Fusarium / metabolism
  • Fusarium / pathogenicity*
  • Plant Diseases / microbiology
  • Trichothecenes / biosynthesis
  • Trichothecenes / genetics
  • Trichothecenes / toxicity*

Substances

  • Trichothecenes