Environmentally friendly sonocatalysis promoted preparation of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles

Lucas Pizzuti; Luciana A Piovesan; Alex F C Flores; Frank H Quina; Claudio M P Pereira

doi:10.1016/j.ultsonch.2009.02.005

Environmentally friendly sonocatalysis promoted preparation of 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles

Ultrason Sonochem. 2009 Aug;16(6):728-31. doi: 10.1016/j.ultsonch.2009.02.005. Epub 2009 Feb 25.

Authors

Lucas Pizzuti¹, Luciana A Piovesan, Alex F C Flores, Frank H Quina, Claudio M P Pereira

Affiliation

¹ Departamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil.

PMID: 19324584
DOI: 10.1016/j.ultsonch.2009.02.005

Abstract

An efficient and green synthesis of thiocarbamoyl-3,5-diaryl-4,5-dihydro-1H-pyrazoles via the condensation of chalcones with thiosemicarbazide in ethanol and KOH under ultrasound irradiation is reported. The products were isolated in good yields after short reaction times.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Ethanol / chemistry
Green Chemistry Technology / methods*
Pyrazoles / chemical synthesis*
Pyrazoles / chemistry
Solvents / chemistry
Sonication
Ultrasonics*

Substances

Pyrazoles
Solvents
Ethanol