Abstract
A short and efficient approach to aza-quaternary pyrrolo[1,2-a]azepine 8 and aza-quaternary indolizine 23, as the crucial intermediates for syntheses of stemonamine (1a) and cephalotaxine (1b), has been developed on the basis of the key intramolecular Schmidt reaction of symmetric azido-diones 5 and 18, respectively.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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4-Butyrolactone / analogs & derivatives*
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4-Butyrolactone / chemical synthesis
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4-Butyrolactone / chemistry
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Azepines / chemical synthesis
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Azepines / chemistry*
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Azides / chemistry*
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Catalysis
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Harringtonines / chemical synthesis*
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Harringtonines / chemistry
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Homoharringtonine
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Magnetic Resonance Spectroscopy
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Molecular Structure
Substances
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Azepines
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Azides
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Harringtonines
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stemonamine
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Homoharringtonine
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4-Butyrolactone