Abstract
We report about a 3-day-old full-term newborn who suffered from series of tonic-clonic and myoclonic seizures. His mother was treated with lamotrigin for epilepsy. It is worthy of note that the drug level of the neonate had already decreas-ed to 37% of the basic level of his mother. At the same time, there was a catabolic metabolic situation and a mild hyponatriaemia. We believe that the neonatal seizures were caused by lamotrigin withdrawal.
Publication types
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Case Reports
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Comparative Study
MeSH terms
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Adult
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Anticonvulsants / adverse effects
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Female
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Humans
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Infant, Newborn
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Lamotrigine
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Male
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Maternal-Fetal Exchange*
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Pregnancy
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Prenatal Exposure Delayed Effects / chemically induced*
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Prenatal Exposure Delayed Effects / diagnosis*
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Prenatal Exposure Delayed Effects / therapy
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Seizures / chemically induced*
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Seizures / diagnosis*
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Seizures / therapy
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Triazines / adverse effects*
Substances
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Anticonvulsants
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Triazines
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Lamotrigine