Design and characterization of a novel indicator dosimeter for blue-light radiation

Med Phys. 2009 Feb;36(2):642-4. doi: 10.1118/1.3039788.

Abstract

Optical absorption and fluorescence measurements have been done on poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene]/[aluminum-tris(8-hydroxyquinoline)] solutions. The authors show that there is a visible response that covers the electronic absorption of bilirubin (350-500 nm), and hence, this material is applicable for managing the radiation doses planning before treatment of jaundice of neonates, which is one of the most common reasons of hospital readmission of newborns infants. The results show that the material presents a gradation of color from orange to yellow clearly, while its peak position emission shifts from orange-red (lambda(max) = 571 nm) to green (lambda(max) = 540 nm) with the radiation exposure time. The rate of these changes can be altered by manipulations of organic solution concentration and they are usually slow (from 2 to 8 h), suggesting these color and emission changes can be used to design an easy to make, easy to read, easy to operate, low cost (< US $0.50) and accuracy for individual monitoring indicator dosimeter in order to represent easily the radiation exposure time usually used in management of neonatal jaundice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption
  • Color
  • Humans
  • Hydroxyquinolines / chemistry
  • Infant, Newborn
  • Jaundice, Neonatal / therapy
  • Light*
  • Phototherapy
  • Polyvinyls / chemistry
  • Radiation Dosage
  • Radiometry / methods*
  • Spectrometry, Fluorescence
  • Time Factors

Substances

  • Hydroxyquinolines
  • Polyvinyls