In this paper the result of application of SIMLII guide lines on upper extremity work related musuloskeletal disorders in different work conditions are presented and discussed. We applied the following risk assessment methods: Washington State Standard, HAL, OCRA, RULA, Strain Index, OREGE. The evaluations were subdivided in 3 class: acceptable risk, intermediate risk, high risk. It is confirmed that the application of more than one method for risk assessment, enable to better measure the risk and to focus the specific risk factors (frequency, posture, force, complementary factors).