Rehabilitation of swallowing with polydimethylsiloxane injections in patients who underwent partial laryngectomy

Head Neck. 2009 Aug;31(8):1022-30. doi: 10.1002/hed.21064.

Abstract

Background: We conducted this longitudinal prospective study to illustrate a surgical technique for swallowing rehabilitation of patients after partial laryngectomy.

Methods: Nine patients with persistent swallowing impairment after partial laryngectomy were included in the study. Evaluation of swallowing was performed by fiberoptic endoscopic evaluation of swallowing (FEES), and was quantified using 2 scales: a dysphagia score and a modified penetration-aspiration scale. The site of bolus inhalation was identified. Polydimethylsiloxane (PDMS) was injected into the neoglottis to fill these passages, and to obtain a certain continence of the organ.

Results: Mean follow-up was 25 months (range, 5-39). All patients showed an improvement both in the dysphagia score and in the modified penetration-aspiration scale. Average improvement was 2.6 points in the dysphagia score (p = .0042) and 2.1 points in the modified penetration-aspiration scale (p = .0043).

Conclusion: PDMS injection can be considered as an option in surgical rehabilitation of swallowing in patients who underwent partial laryngectomy.

MeSH terms

  • Aged
  • Deglutition / drug effects*
  • Deglutition Disorders / drug therapy*
  • Deglutition Disorders / etiology
  • Deglutition Disorders / rehabilitation
  • Dimethylpolysiloxanes / therapeutic use*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Humans
  • Injections, Intralesional
  • Laryngeal Neoplasms / surgery
  • Laryngectomy / adverse effects
  • Laryngectomy / methods*
  • Laryngoscopy / methods
  • Longitudinal Studies
  • Male
  • Patient Satisfaction
  • Probability
  • Prospective Studies
  • Quality of Life*
  • Risk Assessment
  • Statistics, Nonparametric
  • Treatment Outcome

Substances

  • Dimethylpolysiloxanes