Fluidity of eukaryotic genomes

C R Biol. 2009 Feb-Mar;332(2-3):234-40. doi: 10.1016/j.crvi.2008.09.005. Epub 2008 Nov 25.

Abstract

The understanding the different kinds of sequences that make up a genome, as well as their proportions in genomes (obtained by the sequencing of the complete genome), has considerably changed our idea of evolution at the genomic level. The former view of a slowly evolving genome has given way to the idea of a genome that can undergo many transformations, on a large or small scale, depending on the evolution of the different types of sequences constituting it. Here we summarise the evolution of these sequences and the impact it can have on the genome. We have focused on micro-transformations, and especially on the impact of transposable elements on genomes.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Evolution
  • DNA Transposable Elements / genetics
  • Eukaryotic Cells / physiology*
  • Genetic Variation
  • Genome*
  • Humans

Substances

  • DNA Transposable Elements