Abstract
Two new flavonoids, hydroxybenzyl flavonoid glycosides (6-p-hydroxybenzyl kaempferol-7-O-beta-D-glucopyranoside named cudranian 1 and 6-p-hydroxybenzyl quercetin-7-O-beta-D-glucopyranoside named cudranian 2), and 3 known flavonoids (kaempferol-7-O-beta-D-glucopyranoside, quercetin-7-O-beta-D-glucopyranoside and aromadendrin) were isolated from root bark of Cudrania tricuspidata and their structures were elucidated by spectroscopic methods. These compounds showed remarkable radical scavenging effects against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and anti-lipid peroxidation efficacy on human low-density lipoprotein by TBARS assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biphenyl Compounds / chemistry
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Flavonoids / chemistry
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Flavonoids / isolation & purification
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Flavonoids / pharmacology*
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification
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Free Radical Scavengers / pharmacology*
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Humans
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Lipoproteins, LDL / blood
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Lipoproteins, LDL / chemistry
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Molecular Structure
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Moraceae / chemistry*
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Oxidation-Reduction
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Picrates / chemistry
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Plant Bark / chemistry
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Plant Roots / chemistry
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Thiobarbituric Acid Reactive Substances / chemistry
Substances
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Biphenyl Compounds
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Flavonoids
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Free Radical Scavengers
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Lipoproteins, LDL
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Picrates
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Thiobarbituric Acid Reactive Substances
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1,1-diphenyl-2-picrylhydrazyl