Synthesis of deacetyl-1,10-didehydrosalvinorin G

Zhongze Ma; David Y W Lee

doi:10.1016/j.tetlet.2008.01.065

Synthesis of deacetyl-1,10-didehydrosalvinorin G

Tetrahedron Lett. 2008 Mar 10;49(11):1782-1785. doi: 10.1016/j.tetlet.2008.01.065.

Authors

Zhongze Ma¹, David Y W Lee

Affiliation

¹ Bio-Organic and Natural Products Laboratory, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478.

Abstract

To unambiguously confirm the actual product in autoxidation of salvinorin A under basic conditions, deacetyl-1,10-didehydrosalvinorin G was synthesized from salvinorin C via intermediate salvinorin H. Furthermore, oxidation of salvinorin D with manganese dioxide gave salvinorin G in good yield.

Abstract

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