Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy

Chem Commun (Camb). 2009 Mar 28:(12):1475-7. doi: 10.1039/b900427k. Epub 2009 Feb 18.

Abstract

Functionalisation of MSN with mannose for PDT applications dramatically improved the efficiency of PDT on breast cancer cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis
  • Cell Line, Tumor
  • Drug Delivery Systems
  • HeLa Cells
  • Humans
  • Lectins, C-Type / metabolism
  • Mannose / chemistry*
  • Mannose / metabolism
  • Mannose Receptor
  • Mannose-Binding Lectins / metabolism
  • Molecular Structure
  • Nanoparticles / chemistry*
  • Photochemotherapy*
  • Receptors, Cell Surface / metabolism
  • Silicon Dioxide / chemistry*

Substances

  • Lectins, C-Type
  • Mannose Receptor
  • Mannose-Binding Lectins
  • Receptors, Cell Surface
  • Silicon Dioxide
  • Mannose