Abstract
A series of D-glucose derivatives that have been modified at C-4 were synthesised from D-galactose as potential chain terminators of cellulose biosynthesis. Two compounds displayed herbicidal activity in pre-emergence tests and in addition a cell expansion assay at higher concentrations revealed symptomology of a third compound that was indicative of inhibition of cellulose biosynthesis.
MeSH terms
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Cellulose / antagonists & inhibitors*
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Cellulose / biosynthesis*
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Cellulose / chemistry
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Dose-Response Relationship, Drug
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Galactose / chemistry
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Glucose / analogs & derivatives
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Glucose / chemical synthesis*
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Glucose / pharmacology*
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Molecular Structure
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Monosaccharides / chemical synthesis*
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Monosaccharides / chemistry
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Monosaccharides / pharmacology*
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Nicotiana / cytology
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Nicotiana / drug effects
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Nicotiana / metabolism
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Stereoisomerism
Substances
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Monosaccharides
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Cellulose
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Glucose
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Galactose