"Mycobacterium tilburgii," a newly described, uncultivated opportunistic pathogen

Tara N Palmore; Yvonne R Shea; Patricia S Conville; Frank G Witebsky; Victoria L Anderson; Irene P Rupp Hodge; Steven M Holland

doi:10.1128/JCM.02385-08

"Mycobacterium tilburgii," a newly described, uncultivated opportunistic pathogen

J Clin Microbiol. 2009 May;47(5):1585-7. doi: 10.1128/JCM.02385-08. Epub 2009 Mar 4.

Authors

Tara N Palmore¹, Yvonne R Shea, Patricia S Conville, Frank G Witebsky, Victoria L Anderson, Irene P Rupp Hodge, Steven M Holland

Affiliation

¹ Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. tpalmore@mail.nih.gov

Abstract

Molecular methods are increasingly used to identify pathogens that are difficult to cultivate. We report a case of disseminated infection with "Mycobacterium tilburgii," a proposed species that has never been cultivated. The case illustrates the diagnostic utility of sequence analysis of the 16S rRNA gene directly from clinical specimens.

Publication types

Case Reports
Research Support, N.I.H., Extramural

MeSH terms

DNA, Bacterial / genetics
DNA, Ribosomal / genetics
Humans
Jejunum / pathology
Male
Middle Aged
Mycobacterium / classification*
Mycobacterium / isolation & purification*
Mycobacterium Infections / microbiology*
Opportunistic Infections / microbiology*
RNA, Ribosomal, 16S / genetics
Radiography, Abdominal
Sequence Analysis, DNA

Substances

DNA, Bacterial
DNA, Ribosomal
RNA, Ribosomal, 16S