One-pot three-component tandem reaction of diazo compounds with anilines and unsaturated ketoesters: a novel synthesis of 2,3-dihydropyrrole derivatives

Yingguang Zhu; Changwei Zhai; Yongli Yue; Liping Yang; Wenhao Hu

doi:10.1039/b822626a

One-pot three-component tandem reaction of diazo compounds with anilines and unsaturated ketoesters: a novel synthesis of 2,3-dihydropyrrole derivatives

Chem Commun (Camb). 2009 Mar 21:(11):1362-4. doi: 10.1039/b822626a. Epub 2009 Feb 9.

Authors

Yingguang Zhu¹, Changwei Zhai, Yongli Yue, Liping Yang, Wenhao Hu

Affiliation

¹ Advanced Research Center of Drug Discovery and Development, and Department of Chemistry, East China Normal University, 3663 Zhongshan Bei Road, Shanghai 200062, China.

PMID: 19259588
DOI: 10.1039/b822626a

Abstract

A facile synthesis of 2,3-dihydropyrrole derivatives has been achieved through the one-pot, three-component tandem reaction of diazo compounds with anilines and beta,gamma-unsaturated alpha-ketoesters in moderate to good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aniline Compounds / chemistry*
Azo Compounds / chemistry*
Esters / chemistry*
Ketones / chemistry*
Molecular Structure
Pyrroles / chemical synthesis*
Pyrroles / chemistry

Substances

Aniline Compounds
Azo Compounds
Esters
Ketones
Pyrroles
pyrroline
aniline