Appendiceal intussusception is a rare entity that is difficult to diagnosis before surgery both clinically and radiologically. We report here a case of a 55-year-old woman with a 6-month history of right lower abdominal pain caused by appendiceal intussusception. Laparoscopic appendectomy was performed. Endometriosis foci were identified in the appendix tip and became the leading point of the appendiceal intussusception. The appendix was removed laparoscopically, which is the optimal treatment for such patients.