Abstract
A review of 12 patients with proven Aspergillus osteomyelitis was undertaken between July 2004 and October 2007. Aspergillus fumigatus was most commonly identified (n = 9). Voriconazole was commonly administered (11/12; 91.7%), and 9 (75.0%) underwent surgery. Seven (58.3%) responded to treatment, and 12-week mortality was 25.0% (3/12). Survival was improved with surgical intervention (P = 0.05).
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Antifungal Agents / therapeutic use
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Aspergillosis / diagnosis*
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Aspergillosis / drug therapy
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Aspergillosis / microbiology
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Aspergillosis / surgery
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Aspergillus / classification
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Aspergillus / isolation & purification*
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Aspergillus fumigatus / classification
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Aspergillus fumigatus / isolation & purification
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Female
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Humans
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Male
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Middle Aged
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Osteomyelitis / drug therapy
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Osteomyelitis / microbiology*
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Osteomyelitis / mortality
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Osteomyelitis / surgery
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Pyrimidines / therapeutic use
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Treatment Outcome
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Triazoles / therapeutic use
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Voriconazole
Substances
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Antifungal Agents
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Pyrimidines
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Triazoles
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Voriconazole