Evidence for qnrB1 and aac(6')-Ib-cr in CTX-M-15-producing uropathogenic Enterobacteriaceae in an Italian teaching hospital

Mariagrazia Perilli; Chiara Forcella; Giuseppe Celenza; Patrizia Frascaria; Bernardetta Segatore; Cristina Pellegrini; Gianfranco Amicosante

doi:10.1016/j.diagmicrobio.2009.01.009

Evidence for qnrB1 and aac(6')-Ib-cr in CTX-M-15-producing uropathogenic Enterobacteriaceae in an Italian teaching hospital

Diagn Microbiol Infect Dis. 2009 May;64(1):90-3. doi: 10.1016/j.diagmicrobio.2009.01.009. Epub 2009 Feb 26.

Authors

Mariagrazia Perilli¹, Chiara Forcella, Giuseppe Celenza, Patrizia Frascaria, Bernardetta Segatore, Cristina Pellegrini, Gianfranco Amicosante

Affiliation

¹ Dipartimento di Scienze e Tecnologie Biomediche, Università degli Studi dell'Aquila, Italy. perilli@univaq.it

PMID: 19249178
DOI: 10.1016/j.diagmicrobio.2009.01.009

Abstract

In this work, we report the spread of CTX-M-producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6')-Ib-cr, qnrB1, and bla(CTX-M-15) resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aminoglycosides / pharmacology
Anti-Bacterial Agents / pharmacology
Ciprofloxacin / pharmacology
Drug Resistance, Multiple, Bacterial*
Enterobacteriaceae / drug effects*
Enterobacteriaceae / isolation & purification
Enterobacteriaceae Infections / microbiology*
Gene Order
Genes, Bacterial
Hospitals, Teaching
Humans
Italy
Urinary Tract Infections / microbiology*
beta-Lactamases / biosynthesis
beta-Lactams / pharmacology

Substances

Aminoglycosides
Anti-Bacterial Agents
beta-Lactams
Ciprofloxacin
beta-lactamase CTX-M-15
beta-Lactamases