The effect of plant sterols or stanols on lipid parameters in patients with type 2 diabetes: a meta-analysis

William L Baker; Erica L Baker; Craig I Coleman

doi:10.1016/j.diabres.2009.01.015

The effect of plant sterols or stanols on lipid parameters in patients with type 2 diabetes: a meta-analysis

Diabetes Res Clin Pract. 2009 May;84(2):e33-7. doi: 10.1016/j.diabres.2009.01.015. Epub 2009 Feb 24.

Authors

William L Baker¹, Erica L Baker, Craig I Coleman

Affiliation

¹ The Evidence-Based Practice Center, Hartford Hospital, Hartford, CT 06102-5037, United States.

PMID: 19243852
DOI: 10.1016/j.diabres.2009.01.015

Abstract

We performed a meta-analysis of five randomized, placebo-controlled trials to characterize the impact of plant sterols/stanols on plasma lipids in patients with type 2 diabetes. Upon meta-analysis, plant sterols/stanols significantly reduced total and LDL cholesterol, with a trend towards improvement in HDL. No beneficial effect on triglycerides was apparent.

Publication types

Meta-Analysis

MeSH terms

Anticholesteremic Agents / therapeutic use*
Cholesterol / blood
Cholesterol, LDL / blood*
Cholesterol, LDL / drug effects
Diabetes Mellitus, Type 2 / blood*
Diabetes Mellitus, Type 2 / drug therapy
Humans
Lipids / blood*
Phytosterols / therapeutic use*
Randomized Controlled Trials as Topic
Research Design
Sitosterols / therapeutic use*
Triglycerides / blood

Substances

Anticholesteremic Agents
Cholesterol, LDL
Lipids
Phytosterols
Sitosterols
Triglycerides
Cholesterol