Morphological and functional evaluation of visual disturbances in a bilateral hand allograft recipient

J Plast Reconstr Aesthet Surg. 2010 Apr;63(4):700-4. doi: 10.1016/j.bjps.2008.12.033. Epub 2009 Feb 23.

Abstract

Allograft recipients are exposed to risks owing to immunosuppression, and there is always the possibility that psychological issues interfere with the procedure's outcomes. An episode of blindness was suspected in a bilateral hand allograft recipient. The patient underwent a multidisciplinary evaluation, and clinical, electrophysiological, laboratory and a combination of functional and morphological magnetic resonance imaging (MRI) tests ruled out any visual process and revealed a secondary benefit, which turned out to be the use of privileges of the transplant support centre for several months. Composite tissue allograft recipients require a thorough psychological assessment before and after transplant procedures to prevent malingering.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Electroretinography
  • Female
  • Follow-Up Studies
  • Graft Rejection / complications*
  • Graft Rejection / diagnosis
  • Graft Rejection / drug therapy
  • Hand Injuries / surgery*
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Magnetic Resonance Imaging
  • Middle Aged
  • Stress, Psychological / complications*
  • Tissue Transplantation / adverse effects*
  • Transplantation, Homologous
  • Vision Disorders / diagnosis
  • Vision Disorders / etiology*
  • Vision Disorders / physiopathology
  • Visual Acuity / physiology*

Substances

  • Immunosuppressive Agents